Our Mission is to improve the quality of life for people with functional metabolic diseases


MedAutonomic is developing the Phoenix, a Brain NeuroModulator (BNM), that is at the forefront of bioelectric medicines.

The BNM adjusts the balance of the parasympathetic / sympathetic tone in the Autonomic Nervous System, leading to an improvement in health.  A novel non-battery power generation is used to send a precise signal to the brain, and the effectiveness of signaling is measured by heart rate variability (HRV).




MedAutonomic's Phoenix Brain NeuroModulator, an "electroceutical", is implanted in the stomach wall with a gastric endoscope, so no surgery is required.  To our knowledge, we are the only company to have implanted a medical device in the stomach wall with a digestive endoscope.  We have also developed a technology that sends the correct signal to the brain to rebalance the ANS. 

We have successfully done a number of implants of the device on swine and have perfected the implantation procedure (four-five minutes through digestive upper endoscopy).  The prototype BNM is sending a signal to the brain using a piezoelectric energy harvesting technology, so a battery is not required.  After the BNM is implanted we have measured a significant change in the swine's HRV.



At the center of MedAutonomic is Dr. Valerio Cigaina. Dr. Cigaina invented and commercialized the gastric pacemaker, a device that helps people control their eating. Based on years of research, Dr. Cigaina determined that the pacemaker worked by correcting an imbalance in the Autonomic Nervous System (ANS), and that diseases such as type-2 diabetes, hypertension and gastroesophageal reflux disease (GERD) were related to this imbalance. Through data on hundreds of patients, he was able to determine the precise signal that was sent to the brain to correct the ANS imbalance.


The MedAutonomic Team at
San Diego Digestive Disease Week 2016

MedAutonomic's Brain NeuroModulator: Phoenix